Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.57 |
| ▸ | VNN1 | O95497 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463699 | 0.93 | NNMT (0.56) | NNMTVNN1HPGDCRBNADRA1A | |
| SCHEMBL24099729 | 0.91 | NNMT (0.55) | NNMTVNN1HPGDCRBNPDK2 | |
| SCHEMBL22226400 | 0.86 | NNMT (0.64) | NNMTVNN1HPGDCRBNCYP11B2 | |
| SCHEMBL22226404 | 0.83 | NNMT (0.59) | NNMTVNN1HPGDCRBNCYP11B2 | |
| SCHEMBL22226015 | 0.82 | VNN1 (0.44) | NNMTVNN1HPGDPRMT5WDR77 | |
| SCHEMBL22226403 | 0.80 | NNMT (0.61) | NNMTVNN1HPGDCRBNCYP11B2 | |
| SCHEMBL22226928 | 0.76 | NNMT (0.51) | NNMTVNN1CRBN | |
| SCHEMBL22226398 | 0.76 | NNMT (0.51) | NNMTVNN1CRBN | |
| SCHEMBL5306512 | 0.75 | NNMT (0.75) | NNMTCRBN | |
| SCHEMBL25787747 | 0.74 | NNMT (1.00) | NNMTCRBNCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145250-A1 | 15-PGDH INHIBITOR | 杏林製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |