SCHEMBL222262

SCHEMBL222262

CCCCCCCC(N)OCCO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
CYP2D6 P10635 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
SPHK1 Q9NYA1 2/20 0.46
TP53 P04637 2/20 0.46
GMNN O75496 1/20 0.46
POLB P06746 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
BLM P54132 1/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CETP P11597 1/20 0.46
UBE2N P61088 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
THRB P10828 1/20 0.45
OPRM1 P35372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4119313 1.00 LMNA (0.46) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL383218 0.98 OPRM1 (0.43) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL28155567 0.90 CNR2 (0.49) LMNACYP2D6MAPTSPHK1TP53
SCHEMBL29137154 0.90 OPRM1 (0.46) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL28647834 0.90 OPRM1 (0.46) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL22444770 0.90 OPRM1 (0.46) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL28651942 0.90 OPRM1 (0.46) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL9014249 0.89 MEN1 (0.58) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL9014282 0.89 MEN1 (0.58) LMNACYP2D6MAPTHTTSPHK1
SCHEMBL9014265 0.89 MEN1 (0.58) LMNACYP2D6MAPTHTTSPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037836-B1 ULTRASENSITIVE MAGNETIC SENSOR BASED ON GIANT FARADAY ROTATION TOYOTA MOTOR CO LTD (JP) 2017-09-13 EP disclosed
US-9494809-B2 Ultrasensitive magnetic sensor with magneto-optically active material with high verdet constant TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-11-15 US disclosed
EP-3037836-A1 ULTRASENSITIVE MAGNETIC SENSOR BASED ON GIANT FARADAY ROTATION Toyota Jidosha Kabushiki Kaisha (JP) 2016-06-29 EP disclosed
EP-2380029-B1 ULTRASENSITIVE MAGNETIC SENSOR BASED ON GIANT FARADAY ROTATION TOYOTA MOTOR CO LTD (JP) 2015-10-21 EP disclosed
US-20140070802-A1 ULTRASENSITIVE MAGNETIC SENSOR WITH MAGNETO-OPTICALLY ACTIVE MATERIAL WITH HIGH VERDET CONSTANT KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2014-03-13 US disclosed
US-8575927-B2 Ultrasensitive magnetic sensor with magneto-optically active material with high verdet constant TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2013-11-05 US disclosed
US-20120001625-A1 ULTRASENSITIVE MAGNETIC SENSOR BASED ON GIANT FARADAY ROTATION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2012-01-05 US disclosed