Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222262 | 0.98 | LMNA (0.46) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL4119313 | 0.98 | LMNA (0.46) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL22444769 | 0.89 | OPRM1 (0.48) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL3942174 | 0.89 | MEN1 (0.55) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL28155567 | 0.88 | CNR2 (0.49) | LMNACYP2D6MAPTSPHK1TP53 | |
| SCHEMBL9014249 | 0.87 | MEN1 (0.58) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL28783949 | 0.87 | MEN1 (0.58) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL10561047 | 0.87 | MEN1 (0.58) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL9014282 | 0.87 | MEN1 (0.58) | OPRM1LMNACYP2D6MAPTHTT | |
| SCHEMBL9014265 | 0.87 | MEN1 (0.58) | OPRM1LMNACYP2D6MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370605-B1 | POROUS CARBONS | BRITISH AMERICAN TOBACCO CO (GB) | 2012-01-25 | — | — | EP | disclosed |