Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229422 | 0.73 | MITF (0.46) | PKMMITFLMNAKMT2AALDH1A1 | |
| SCHEMBL2223253 | 0.72 | ALDH1A1 (0.37) | PKMMITFKMT2AALDH1A1 | |
| SCHEMBL13595500 | 0.68 | CA1 (0.41) | CASRCA1KMT2A | |
| SCHEMBL6681523 | 0.67 | MITF (0.40) | PKMMITFLMNAKMT2AALDH1A1 | |
| SCHEMBL13573054 | 0.66 | CA1 (0.41) | MAPK1CASRCA1KMT2AALDH1A1 | |
| SCHEMBL1227861 | 0.66 | PRMT5 (0.48) | PKMCYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13595460 | 0.65 | CA1 (0.38) | CASRCA1KMT2A | |
| SCHEMBL13595496 | 0.65 | CA1 (0.38) | CASRCA1KMT2A | |
| SCHEMBL8820518 | 0.65 | CA1 (0.39) | CASRCA1KMT2APOLB | |
| SCHEMBL25239793 | 0.65 | PPARA (0.45) | CA1ALDH1A1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087995-A2 | ORGANIC COMPOUNDS | BARRY CLIFTON (US) | 2011-07-21 | — | — | WO | disclosed |