SCHEMBL2222665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2221639	0.93	KMT2A (0.60)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2221503	0.89	MEN1 (0.56)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2221486	0.89	MEN1 (0.72)	MEN1KMT2AGAACXCR3MAPT
	SCHEMBL2220801	0.89	WDR5 (0.54)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2221797	0.89	KMT2A (0.53)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2222538	0.89	MEN1 (0.55)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2221554	0.89	MEN1 (0.55)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2222754	0.88	KMT2A (0.52)	MEN1KMT2ATDP1GAACXCR3
	SCHEMBL2222596	0.88	MAPT (0.56)	MEN1KMT2AGAACXCR3WDR5
	SCHEMBL2221353	0.88	MEN1 (0.54)	MEN1KMT2AGAACXCR3WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.