SCHEMBL2222754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2222734	0.92	KMT2A (0.52)	KMT2AMEN1APOBEC3GAPOBEC3AHTT
	SCHEMBL2221639	0.90	KMT2A (0.60)	KMT2AMEN1HTTMCL1WDR5
	SCHEMBL2222665	0.88	MEN1 (0.56)	KMT2AMEN1HTTMCL1WDR5
	SCHEMBL2221503	0.86	MEN1 (0.56)	KMT2AMEN1APOBEC3GAPOBEC3AWDR5
	SCHEMBL2222752	0.86	KMT2A (0.52)	KMT2AMEN1APOBEC3GAPOBEC3AHTT
	SCHEMBL2221486	0.86	MEN1 (0.72)	KMT2AMEN1GAAALDH1A1CXCR3
	SCHEMBL2220801	0.86	WDR5 (0.54)	KMT2AMEN1WDR5GAAALDH1A1
	SCHEMBL2221797	0.86	KMT2A (0.53)	KMT2AMEN1HTTWDR5GAA
	SCHEMBL2222538	0.85	MEN1 (0.55)	KMT2AMEN1WDR5GAACXCR3
	SCHEMBL2221554	0.85	MEN1 (0.55)	KMT2AMEN1HTTMCL1WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.