SCHEMBL2222698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2224886	0.87	MEN1 (0.50)	KDM4EPOLBALDH1A1MAPTLMNA
	SCHEMBL2222103	0.86	MEN1 (0.41)	KDM4EPOLBALDH1A1HPGDMAPT
	SCHEMBL12517064	0.85	CCR5 (0.43)	KDM4EPOLBALDH1A1MAPTLMNA
	SCHEMBL2225222	0.84	POLB (0.47)	POLBALDH1A1MAPTMEN1KMT2A
	SCHEMBL2223740	0.83	CCR5 (0.47)	KDM4EALDH1A1HPGDMAPTLMNA
	SCHEMBL2222816	0.82	CCR5 (0.46)	KDM4EPOLBMAPTLMNAMEN1
	SCHEMBL2222490	0.82	MEN1 (0.39)	KDM4EPOLBALDH1A1MAPTLMNA
	SCHEMBL2223966	0.82	CYP2C9 (0.44)	KDM4EPOLBALDH1A1MAPTMEN1
	SCHEMBL2221969	0.82	KDM4E (0.50)	KDM4EPOLBALDH1A1MAPTLMNA
	SCHEMBL2225476	0.82	ALDH1A1 (0.46)	KDM4EALDH1A1MAPTLMNASRPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.