SCHEMBL2222705

SCHEMBL2222705

CC(CN)=C(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.43
CYP19A1 P11511 1/20 0.40
ESR2 Q92731 1/20 0.40
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
PTGS2 P35354 1/20 0.37
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
F12 P00748 1/20 0.37
F7 P08709 1/20 0.37
F3 P13726 1/20 0.37
PKM P14618 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11388068 0.84 HPGD (0.56) ESR1CYP19A1ESR2L3MBTL1LMNA
SCHEMBL7712236 0.84 ESR1 (0.42) ESR1CYP19A1ESR2CES2CES1
SCHEMBL18591420 0.79 HDAC1 (0.42) ESR1CYP19A1ESR2HDAC1HDAC2
SCHEMBL18591419 0.79 HDAC1 (0.42) ESR1CYP19A1ESR2HDAC1HDAC2
SCHEMBL2767079 0.78 ATM (0.48) ESR1CYP19A1ESR2CES2CES1
SCHEMBL2767081 0.78 ATM (0.48) ESR1CYP19A1ESR2CES2CES1
SCHEMBL2172813 0.78 ESR1 (0.45) ESR1CYP19A1HDAC1HDAC2CES2
SCHEMBL2172806 0.78 ESR1 (0.45) ESR1CYP19A1HDAC1HDAC2CES2
Hydrochloric Acid SCHEMBL18555485 0.77 HDAC1 (0.41) ESR1CYP19A1ESR2HDAC1HDAC2
Hydrochloric Acid SCHEMBL18578766 0.77 HDAC1 (0.41) ESR1CYP19A1ESR2HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783671-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters Fachhochschule Münster (DE) 2017-10-10 US claimed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP claimed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO claimed
US-9803091-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on vinyl esters and vinyl ester urethanes Fachhochschule Münster (DE) 2017-10-31 US disclosed
US-9783671-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters Fachhochschule Münster (DE) 2017-10-10 US disclosed
EP-2951245-B1 CROSSLINKED PLASTIC MATERIAL WITH INTRINSIC ANTIMICROBIAL EFFECT ON THE BASIS OF UNSATURATED POLYESTER Fachhochschule Münster (DE) 2017-08-02 EP disclosed
EP-2951243-B1 CROSSLINKED PLASTIC MATERIAL WITH INTRINSICALLY ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTERURETHANES Fachhochschule Münster (DE) 2017-03-08 EP disclosed
US-20170049801-A1 MULTIBLOCK COPOLYMERS UNIVERSITY OF WASHINGTON (US) 2017-02-23 US disclosed
US-20150361259-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON UNSATURATED POLYESTERS Fachhochschule Münster (DE) 2015-12-17 US disclosed
US-20150361277-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTER URETHANES Fachhochschule Münster (DE) 2015-12-17 US disclosed
EP-2951243-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSICALLY ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTER URETHANES Fachhochschule Münster (DE) 2015-12-09 EP disclosed
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
US-20040208834-A1 Oral-use polymer and oral-use composition KAO CORPORATION (JP) 2004-10-21 US disclosed
EP-1413589-A1 POLYMERS FOR ORAL USE AND COMPOSITIONS FOR ORAL USE Kao Corporation (JP) 2004-04-28 EP disclosed
US-20030129520-A1 Using graft polymer on etched or anodized aluminum substrate FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed
US-6361768-B1 POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER PMD HOLDINGS CORP. 2002-03-26 US disclosed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP disclosed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170049801-A1 MULTIBLOCK COPOLYMERS ABCB4, CD47, MCL1 ESR1 2243/4885CYP19A1 4414/4885ESR2 2770/4885
US-20040208834-A1 Oral-use polymer and oral-use composition PHOSPHO1, PPA1, PHPT1 ESR1 2692/4885CYP19A1 4120/4885ESR2 2715/4885
US-20150361259-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON UNSATURATED POLYESTERS PUF60, FASN, ALOX5 ESR1 1210/4885CYP19A1 1962/4885ESR2 2332/4885
US-20150361277-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTER URETHANES PUF60, UROD, MYD88 ESR1 769/4885CYP19A1 2115/4885ESR2 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.