Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22227689 | 1.00 | RORC (0.85) | RORC | |
| SCHEMBL22227722 | 0.96 | RORC (0.82) | RORC | |
| SCHEMBL22227723 | 0.96 | RORC (0.82) | RORC | |
| SCHEMBL22227720 | 0.94 | RORC (0.83) | RORC | |
| SCHEMBL22227710 | 0.94 | RORC (0.88) | RORC | |
| SCHEMBL22227709 | 0.94 | RORC (0.88) | RORC | |
| SCHEMBL22227721 | 0.94 | RORC (0.83) | RORC | |
| SCHEMBL22227726 | 0.94 | RORC (0.89) | RORC | |
| SCHEMBL22227697 | 0.94 | RORC (0.84) | RORC | |
| SCHEMBL22227698 | 0.94 | RORC (0.84) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963836-B | Deuterium atom substituted indole carboxamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-20200277278-A1 | Deuterium Atom-Substituted Indole Formamide Derivative, Preparation Method Therefor, and Medical Applications Thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| EP-3683206-A1 | DEUTERIUM ATOM-SUBSTITUTED INDOLE FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATIONS THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2020-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277278-A1 | Deuterium Atom-Substituted Indole Formamide Derivative, Preparation Method Therefor, and Medical Applications Thereof | RORA, RORB, RORC | RORC 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.