SCHEMBL222287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1359189	0.91	CYP11B1 (0.51)	CYP11B1CYP11B2MAPTCYP2A6MEN1
	SCHEMBL77083	0.84	TDP1 (0.67)	CYP11B1CYP11B2MAPTCYP2A6MEN1
	SCHEMBL29580441	0.84	TDP1 (0.67)	CYP11B1CYP11B2MAPTCYP2A6MEN1
	SCHEMBL5036431	0.83	CHEK2 (0.50)	CYP11B1CYP11B2CYP2A6MEN1PSIP1
	SCHEMBL1358710	0.83	CYP2A6 (0.51)	CYP11B1CYP11B2MAPTCYP2A6RAB9A
	SCHEMBL223120	0.82	ABCB1 (0.52)	CYP11B1CYP11B2MAPTMEN1MKNK1
	SCHEMBL1663904	0.82	CYP11B1 (0.57)	CYP11B1CYP11B2CYP2A6MEN1PSIP1
	SCHEMBL12239777	0.81	CYP2A6 (0.43)	CYP11B1CYP11B2MAPTCYP2A6MEN1
	SCHEMBL12818449	0.79	CRHBP (0.67)	MAPTMEN1ALDH1A1CYP3A4ABCB1
	SCHEMBL1862024	0.79	HDAC3 (0.48)	CYP11B1CYP11B2MAPTMEN1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.