Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580441 | 1.00 | TDP1 (0.67) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL1663904 | 0.86 | CYP11B1 (0.57) | MEN1CYP11B1CYP11B2PSIP1AXL | |
| SCHEMBL222287 | 0.84 | CYP11B1 (0.55) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL30474720 | 0.83 | MAPT (0.73) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL717629 | 0.83 | MAPT (0.73) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL4704336 | 0.82 | ERN1 (0.56) | MAPTCYP11B1CYP11B2MKNK1MKNK2 | |
| SCHEMBL2377563 | 0.82 | DAPK3 (0.56) | MAPTMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL1980117 | 0.82 | CYP11B1 (0.51) | MAPTMEN1CYP11B1CYP11B2PSIP1 | |
| Hydrochloric Acid SCHEMBL3973011 | 0.82 | MAPT (0.92) | TDP1MAPTMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL3973012 | 0.82 | MAPT (0.92) | TDP1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136570-A1 | HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| US-20240376059-A1 | Compounds for the Treatment of Alzheimer's Disease | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2024-11-14 | — | — | US | disclosed |
| EP-4441033-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. (US) | 2024-10-09 | — | — | EP | disclosed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-11939302-B2 | Compounds for the treatment of Alzheimer's disease | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2024-03-26 | — | — | US | disclosed |
| EP-4232438-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | The Governors of the University of Alberta (CA) | 2023-08-30 | — | — | EP | disclosed |
| WO-2023102162-A1 | TGONOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20230174501-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230174501-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
| EP-0960103-A1 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5948797-A | ANTITUMOR AGENT | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998031673-A9 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | — | 1998-12-10 | — | — | WO | disclosed |
| US-5807874-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1998031673-A1 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5770617-A | Terbenzimidazoles useful as antifungal agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5767142-A | INHIBITION OF MAMMALIAN TUMOR CELL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0839140-A1 | TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1996036612-A1 | TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1996-11-21 | — | — | WO | disclosed |
| US-4297362-A | 4-(3,4-Diaminophenyl)pyridine or salts, and use thereof as cardiotonic | STERLING DRUG INC. (US) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174501-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | HDAC1, HDAC7, HDAC5 | TDP1 997/4885MAPT 2684/4885MEN1 4054/4885 |
| US-20240376059-A1 | Compounds for the Treatment of Alzheimer's Disease | IAPP, GPR119, APP | TDP1 1690/4885MAPT 80/4885MEN1 1321/4885 |
| US-20250136570-A1 | HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | HDAC1, HDAC7, HDAC5 | TDP1 846/4885MAPT 2829/4885MEN1 3551/4885 |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | HDAC1, HDAC7, HDAC5 | TDP1 846/4885MAPT 2829/4885MEN1 3551/4885 |
| US-11939302-B2 | Compounds for the treatment of Alzheimer's disease | IAPP, GPR119, APP | TDP1 1690/4885MAPT 80/4885MEN1 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.