Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815055 | 0.81 | GABBR2 (0.53) | ALDH1A1GABBR2GABBR1MAPTMEN1 | |
| SCHEMBL1114871 | 0.81 | ALDH1A1 (0.56) | ALDH1A1GLATSHRMAPTMEN1 | |
| Alcohol SCHEMBL28575312 | 0.78 | GABBR2 (0.66) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL503819 | 0.78 | GABBR2 (0.76) | TSHRGABBR2GABBR1MAPTMEN1 | |
| SCHEMBL20369046 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GLATSHRMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7092228 | 0.76 | GABBR2 (0.73) | TSHRGABBR2GABBR1MAPTMEN1 | |
| SCHEMBL6734410 | 0.76 | GABBR2 (0.73) | TSHRGABBR2GABBR1MAPTMEN1 | |
| SCHEMBL308738 | 0.75 | ALDH1A1 (0.66) | ALDH1A1GLATSHRMAPTMEN1 | |
| SCHEMBL2484805 | 0.75 | GABBR2 (0.66) | TSHRGABBR2GABBR1MAPTMEN1 | |
| SCHEMBL2030599 | 0.75 | ALDH1A1 (0.70) | ALDH1A1GLATSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086565-A1 | METHOD FOR PREPARATION OF ENANTIOMERICALLY ENRICHED AND/OR RACEMIC GAMMA-AMINO ACIDS | LUPIN LIMITED (IN) | 2011-07-21 | — | — | WO | disclosed |