SCHEMBL22229003

SCHEMBL22229003

O=C(O[PH](=O)c1ccccc1)c1c(Cl)cccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
PTK2B Q14289 1/20 0.44
ALDH1A1 P00352 3/20 0.42
TXNRD1 Q16881 1/20 0.39
FEN1 P39748 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
PBRM1 Q86U86 1/20 0.37
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.36
APAF1 O14727 1/20 0.36
TDP2 O95551 1/20 0.36
NSD2 O96028 1/20 0.36
ABL1 P00519 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
RIN1 Q13671 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2702064 0.77 CA12 (0.53) ALDH1A1LMNAKMT2AMEN1NPSR1
SCHEMBL21840795 0.76 LMNA (0.52) MAPTALDH1A1TDP1LMNAKMT2A
SCHEMBL7620994 0.76 FEN1 (0.46) MAPTPTK2BALDH1A1TXNRD1FEN1
SCHEMBL2840836 0.73 ALDH1A1 (0.36) ALDH1A1L3MBTL1LMNAKDM4EKMT2A
SCHEMBL8425238 0.73 ALDH1A1 (0.47) MAPTPTK2BALDH1A1FEN1PBRM1
SCHEMBL29169972 0.72 ALDH1A1 (0.35) ALDH1A1L3MBTL1LMNAKDM4EKMT2A
SCHEMBL22611949 0.71 RXRA (0.37) MAPTALDH1A1L3MBTL1TDP1RAB9A
SCHEMBL5703139 0.71 ALDH1A1 (0.58) MAPTPTK2BALDH1A1TXNRD1FEN1
SCHEMBL28340585 0.71 ALDH1A1 (0.58) MAPTPTK2BALDH1A1TXNRD1FEN1
SCHEMBL8638289 0.70 ALDH1A1 (0.52) MAPTPTK2BALDH1A1TXNRD1FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11945891-B2 Speaker having an adhesive composition DENKA COMPANY LIMITED (JP) 2024-04-02 US disclosed
US-20200231726-A1 COMPOSITION DENKA COMPANY LIMITED (JP) 2020-07-23 US disclosed