SCHEMBL2222928

SCHEMBL2222928

O=Cc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
CYP2A6 P11509 2/20 0.62
CALM1 P0DP23 1/20 0.60
PLA2G10 O15496 1/20 0.48
PLA2G2A P14555 1/20 0.48
LMNA P02545 1/20 0.48
LTA4H P09960 2/20 0.47
ELANE P08246 1/20 0.46
RAB9A P51151 1/20 0.46
IDH1 O75874 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL28055727 0.92 ALDH1A1 (0.74) ALDH1A1CYP2A6CALM1PLA2G10PLA2G2A
SCHEMBL3976211 0.89 CYP2A6 (0.52) ALDH1A1CYP2A6LMNARAB9AHSD17B10
SCHEMBL14369268 0.88 ALDH1A1 (0.59) ALDH1A1CYP2A6CALM1RAB9AMAOA
SCHEMBL2226596 0.88 ALDH1A1 (0.59) ALDH1A1CYP2A6CALM1RAB9AMAOA
SCHEMBL2225297 0.84 ALDH1A1 (0.54) ALDH1A1CYP2A6MAOAMAOB
Tannin Pyrogallol SCHEMBL28661466 0.84 ALDH1A1 (0.61) ALDH1A1CYP2A6CALM1PLA2G10PLA2G2A
SCHEMBL17278365 0.84 ALDH1A1 (0.54) ALDH1A1CYP2A6MAOAMAOB
SCHEMBL2323602 0.84 HDAC8 (0.59) ALDH1A1CYP2A6MAOACA1CA2
SCHEMBL3079479 0.83 CA12 (0.45) ALDH1A1CYP2A6CALM1PLA2G10PLA2G2A
SCHEMBL7369619 0.82 TSHR (0.62) ALDH1A1CYP2A6LMNALTA4HRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791374-A Photosensitizer with anthraquinone aggregation-induced emission characteristic and preparation method thereof 广西大学 2024-10-18 CN claimed
CN-108440357-A Double arylsulfonium salts class compounds of novel base class containing talan and the preparation method and application thereof 同济大学 2018-08-24 CN claimed
CN-101423520-A Method for synthesizing dibenzylidene sorbitol and dibenzylidene eutrit XINJIANG TECH INST PHYSICS CAS (CN) 2009-05-06 CN claimed
WO-2008010061-A2 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION GLENMARK PHARMACEUTICALS S.A. (US) 2008-01-24 WO claimed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US claimed
US-4345072-A Process for the production of 5-arylidene hydantoins (B) DEGUSSA AG (DE) 1982-08-17 US claimed
CN-118791374-A Photosensitizer with anthraquinone aggregation-induced emission characteristic and preparation method thereof 广西大学 2024-10-18 CN disclosed
CN-118791374-A Photosensitizer with anthraquinone aggregation-induced emission characteristic and preparation method thereof 广西大学 2024-10-18 CN disclosed
EP-3615515-B1 PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF AVIARA PHARMACEUTICALS INC (US) 2024-09-25 EP disclosed
CN-117861616-A Adsorbent, method and system for purifying chlorosilane 新特能源股份有限公司 2024-04-12 CN disclosed
CN-108929308-B Condensed cyclic compound and organic light-emitting device including the same 三星显示有限公司 2023-10-24 CN disclosed
CN-116854558-A Linear non-conjugated cluster luminescent molecule and preparation and application thereof 浙江大学杭州国际科创中心 2023-10-10 CN disclosed
CN-113861130-A Biphenyl sulfanilamide thiadiazole derivative and application thereof in antitumor drugs 守恒(厦门)医疗科技有限公司 2021-12-31 CN disclosed
EP-0037479-B1 PROCESS FOR THE PREPARATION OF 5-ARYLIDENEHYDANTOINS Degussa Aktiengesellschaft (DE) 1983-03-30 EP disclosed
US-4345072-A Process for the production of 5-arylidene hydantoins (B) DEGUSSA AG (DE) 1982-08-17 US disclosed
EP-0037479-A1 Process for the preparation of 5-arylidenehydantoins Degussa Aktiengesellschaft (DE) 1981-10-14 EP disclosed
EP-0037480-A1 Process for the preparation of 5-arylidenehydantoins Degussa Aktiengesellschaft (DE) 1981-10-14 EP disclosed
US-4202894-A AGRICULTURE HOFFMANN-LA ROCHE INC. (US) 1980-05-13 US disclosed
US-4036861-A OXIDATION OF A DIPHENYLMETHANE, VANADIUM OXIDE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-07-19 US disclosed
US-3966678-A Maleic anhydride-polyaldimine prepolymers RHONE-POULENC S.A. (FR) 1976-06-29 US disclosed