Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31223729 | 1.00 | LOXL2 (0.52) | LOXL2SLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL1677867 | 1.00 | LOXL2 (0.52) | LOXL2SLC6A2SLC6A4SLC6A3HRH1 | |
| Bromide SCHEMBL18191799 | 0.98 | LOXL2 (0.50) | LOXL2SLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL10397794 | 0.88 | HRH1 (0.52) | LOXL2HRH1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL9519950 | 0.88 | HRH1 (0.52) | LOXL2HRH1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL19090267 | 0.83 | LOXL2 (0.48) | LOXL2HRH1CYP19A1ANPEPERAP2 | |
| SCHEMBL7187149 | 0.82 | LOXL2 (0.56) | LOXL2HRH1ANPEPERAP2ERAP1 | |
| SCHEMBL3169969 | 0.82 | LOXL2 (0.50) | LOXL2HRH1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL6996146 | 0.80 | LOXL2 (0.50) | LOXL2HRH1CYP19A1ANPEPERAP2 | |
| Hydrazine SCHEMBL2567860 | 0.79 | LOXL2 (0.48) | LOXL2HRH1CYP19A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | BET1, BACH1, POLL | LOXL2 4671/4885SLC6A2 4825/4885SLC6A4 4873/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | LOXL2 4802/4885SLC6A2 4865/4885SLC6A4 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.