SCHEMBL2223053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19831677	0.95	DRD2 (0.60)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL12516846	0.95	DRD2 (0.60)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL12516842	0.95	DRD2 (0.60)	DRD2DRD4DRD3ALDH1A1GMNN
	Hydrochloric Acid SCHEMBL14632762	0.94	DRD2 (0.59)	DRD2DRD4DRD3ALDH1A1GMNN
	Hydrochloric Acid SCHEMBL2223967	0.94	DRD2 (0.59)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL2224530	0.93	DRD2 (0.47)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL2221522	0.91	DRD2 (0.55)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL2222878	0.90	DRD2 (0.52)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL2225901	0.90	LMNA (0.53)	DRD2DRD4DRD3ALDH1A1GMNN
	SCHEMBL2223452	0.90	LMNA (0.50)	DRD2DRD4DRD3ALDH1A1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.