SCHEMBL2223322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2222544	0.92	CYP3A4 (0.46)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2226273	0.92	MAPT (0.48)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2223312	0.91	MAPT (0.56)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2223438	0.91	MAPT (0.53)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2222361	0.91	MAPT (0.53)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2222402	0.90	KCNH2 (0.60)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	Hydrochloric Acid SCHEMBL2223353	0.89	MAPT (0.52)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2226562	0.89	MAPT (0.55)	MAPTTP53LMNAHTTSMN1; SMN2
	SCHEMBL14353883	0.89	CYP3A4 (0.50)	MAPTCYP3A4CYP2D6DRD2SLC6A2
	SCHEMBL2226307	0.88	KCNH2 (0.49)	MAPTCYP3A4CYP2D6DRD2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.