⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14914729 | 0.82 | KDM4E (0.46) | — | |
| SCHEMBL13825564 | 0.82 | BACE1 (0.42) | — | |
| SCHEMBL9983523 | 0.75 | BACE1 (0.41) | — | |
| SCHEMBL2222093 | 0.64 | CYP1A2 (0.63) | — | |
| SCHEMBL19582874 | 0.64 | HTR7 (0.32) | — | |
| SCHEMBL2223356 | 0.62 | PDE10A (0.33) | — | |
| SCHEMBL4715740 | 0.61 | CCR1 (0.32) | — | |
| SCHEMBL4715438 | 0.61 | TERT (0.34) | — | |
| SCHEMBL3387689 | 0.60 | KDM4E (0.37) | — | |
| SCHEMBL508438 | 0.60 | GBA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993767-B2 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-31 | — | — | US | disclosed |
| EP-2523937-B1 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NAT RECH SCIENT (FR) | 2015-03-11 | — | — | EP | disclosed |
| US-20130116281-A1 | Multiphoton Activable Quinoline Derivatives, Their Preparation and Their Uses | UNIVERSITÉ PARIS CITÉ (FR) | 2013-05-09 | — | — | US | disclosed |
| EP-2523937-A1 | MULTIPHOTON ACTIVABLE QUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USES | Centre National De La Recherche Scientifique (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086469-A1 | MULTIPHOTON ACTIVABLE QUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-07-21 | — | — | WO | disclosed |