Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223359 | 0.82 | — | — | |
| SCHEMBL13825564 | 0.82 | BACE1 (0.42) | BACE1CYP3A4 | |
| SCHEMBL9983523 | 0.75 | BACE1 (0.41) | HTTBACE1 | |
| SCHEMBL3387689 | 0.73 | KDM4E (0.37) | KDM4EPOLBMEN1ADRA2AKMT2A | |
| SCHEMBL15472863 | 0.71 | PLAU (0.57) | KDM4ELMNAPOLBCASP6PLAU | |
| SCHEMBL6179382 | 0.70 | NOS3 (0.38) | — | |
| Hydrochloric Acid SCHEMBL28612763 | 0.69 | PLAU (0.55) | KDM4ELMNAPOLBCASP6PLAU | |
| SCHEMBL2927122 | 0.69 | KDM4E (0.51) | KDM4ELMNAPOLBCASP6PLAU | |
| SCHEMBL2927481 | 0.67 | KDM4E (0.49) | KDM4ELMNAPOLBCASP6PLAU | |
| SCHEMBL4406050 | 0.67 | ALDH1A1 (0.44) | KDM4EPOLBMEN1ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993767-B2 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-31 | — | — | US | disclosed |
| EP-2523937-B1 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NAT RECH SCIENT (FR) | 2015-03-11 | — | — | EP | disclosed |
| US-20130116281-A1 | Multiphoton Activable Quinoline Derivatives, Their Preparation and Their Uses | UNIVERSITÉ PARIS CITÉ (FR) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116281-A1 | Multiphoton Activable Quinoline Derivatives, Their Preparation and Their Uses | NQO2, ACHE, NQO1 | KDM4E 2288/4885LMNA 2819/4885POLB 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.