⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18955355 | 0.73 | — | — | |
| SCHEMBL3892310 | 0.70 | — | — | |
| SCHEMBL9010414 | 0.68 | — | — | |
| SCHEMBL3546450 | 0.68 | — | — | |
| SCHEMBL4331588 | 0.68 | — | — | |
| SCHEMBL5496826 | 0.68 | — | — | |
| SCHEMBL31187610 | 0.63 | — | — | |
| SCHEMBL2269769 | 0.62 | ALOX15 (0.31) | — | |
| SCHEMBL11971177 | 0.58 | — | — | |
| SCHEMBL2210400 | 0.49 | MAOA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034173-A1 | PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2025-01-30 | — | — | US | disclosed |
| US-20240336631-A1 | Pyrido[4,3-d]pyrimidine Compounds | PFIZER INC. (US) | 2024-10-10 | — | — | US | disclosed |
| EP-4430035-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 Pharma LLC (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |
| US-8703992-B2 | Method for producing aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxylic acid amides | BASF SE (DE) | 2014-04-22 | — | — | US | disclosed |
| US-20110172456-A1 | Method for Producing Aromatic and Heteroaromatic Carboxylic Acids, Carboxylic Acid Esters and Carboxylic Acid Amides | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |