SCHEMBL4331588

SCHEMBL4331588

CC(C)C1C=Cn2cccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2223382 0.68
SCHEMBL18955355 0.68
SCHEMBL5496826 0.64
SCHEMBL9010414 0.64
SCHEMBL3546450 0.64
SCHEMBL3892310 0.62
SCHEMBL31187610 0.59
SCHEMBL26997414 0.53 MGLL (0.30)
SCHEMBL5597184 0.50 SIGMAR1 (0.41)
SCHEMBL14081795 0.48 PTPN2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776496-A Ultrasmall porous particles for enhancing ultrasound back scatter UNIVERSITY OF ROCHESTER (US) 1998-07-07 US claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
EP-0169618-B2 Method for making uniformly sized particles from water-insoluble organic compounds STERILIZATION TECHN SERV (US) 1993-11-10 EP claimed
EP-0169618-B1 METHOD FOR MAKING UNIFORMLY SIZED PARTICLES FROM WATER-INSOLUBLE ORGANIC COMPOUNDS STERILIZATION TECHNICAL SERVICES, Inc. (US) 1990-08-29 EP claimed
US-4826689-A PRECIPITATION FROM SOLUTION IN ORGANIC SOLVENT UNIVERSITY OF ROCHESTER (US) 1989-05-02 US claimed
US-4734423-A Method of solid cancer tumor treatment using isopropylpyrrolizine derivative THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1988-03-29 US claimed
EP-0169618-A2 Method for making uniformly sized particles from water-insoluble organic compounds STERILIZATION TECHNICAL SERVICES, Inc. (US) 1986-01-29 EP claimed
EP-4746875-A2 CARCINOGENESIS REDUCTION WITH PENTAAZA MACROCYCLIC RING COMPLEX Galera Labs, LLC (US) 2026-05-27 EP disclosed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US disclosed
US-20260108480-A1 METHODS FOR INDUCING PROLIFERATION OF STEM CELLS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-04-23 US disclosed
EP-3921420-B1 DRUG DELIVERY COMPOSITIONS FOR OCULAR ADMINISTRATION OF THERAPEUTICS AND METHODS OF USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-04-08 EP disclosed
US-20260069541-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 US disclosed
US-20260053737-A1 METHODS AND COMPOSITIONS FOR SUSTAINED RELEASE MICROPARTICLES FOR OCULAR DRUG DELIVERY OHIO STATE INNOVATION FOUNDATION (US) 2026-02-26 US disclosed
EP-0544657-A1 METHOD FOR MAKING UNIFORMLY-SIZED PARTICLES FROM INSOLUBLE COMPOUNDS THE UNIVERSITY OF ROCHESTER (US) 1993-06-09 EP disclosed
WO-1993000933-A1 ULTRASMALL NON-AGGREGATED POROUS PARTICLES ENTRAPPING GAS-BUBBLES UNIVERSITY OF ROCHESTER (US) 1993-01-21 WO disclosed
WO-1992003380-A1 METHOD FOR MAKING UNIFORMLY-SIZED PARTICLES FROM INSOLUBLE COMPOUNDS THE UNIVERSITY OF ROCHESTER (US) 1992-03-05 WO disclosed
US-4997454-A Precipitation THE UNIVERSITY OF ROCHESTER (US) 1991-03-05 US disclosed
US-4734423-A Method of solid cancer tumor treatment using isopropylpyrrolizine derivative THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1988-03-29 US disclosed
US-4734423-A Method of solid cancer tumor treatment using isopropylpyrrolizine derivative THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1988-03-29 US disclosed
US-4734423-A Method of solid cancer tumor treatment using isopropylpyrrolizine derivative THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1988-03-29 US disclosed