Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29259455 | 0.84 | MEN1 (0.35) | MEN1KMT2AL3MBTL1MAPTCYP2C9 | |
| SCHEMBL22207434 | 0.83 | CYP1A2 (0.35) | MEN1KMT2AL3MBTL1MAPTCYP2C9 | |
| SCHEMBL20641237 | 0.83 | GAA (0.37) | MEN1KMT2AL3MBTL1MAPTCYP2C9 | |
| SCHEMBL3934630 | 0.81 | ALDH1A1 (0.32) | MEN1KMT2AL3MBTL1MAPTCYP2C9 | |
| SCHEMBL2804353 | 0.80 | HCAR3 (0.38) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL18421834 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL21854406 | 0.80 | CYP1A2 (0.33) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL5578038 | 0.80 | HCAR3 (0.33) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL30079004 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2AL3MBTL1MAPTCYP2C9 | |
| SCHEMBL28492553 | 0.79 | MCL1 (0.37) | MEN1KMT2AL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |