Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18421834 | 0.84 | ALDH1A1 (0.33) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL21854406 | 0.84 | CYP1A2 (0.33) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL5578038 | 0.84 | HCAR3 (0.33) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL22236183 | 0.84 | MEN1 (0.41) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL29259924 | 0.82 | CYP1A2 (0.31) | CYP1A2HPGD | |
| SCHEMBL31413839 | 0.79 | ALDH1A1 (0.34) | KMT2ACYP2C19ALDH1A1PDE8B | |
| SCHEMBL22207434 | 0.78 | CYP1A2 (0.35) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL20641237 | 0.78 | GAA (0.37) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL4284333 | 0.76 | L3MBTL1 (0.38) | MEN1KMT2AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL3934630 | 0.76 | ALDH1A1 (0.32) | MEN1KMT2AL3MBTL1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063457-A | Pyridone compounds, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |