Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 18/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236835 | 0.88 | CYP11B2 (0.74) | CYP11B2 | |
| SCHEMBL27132479 | 0.74 | CYP11B2 (0.84) | CYP11B2 | |
| SCHEMBL18508452 | 0.74 | CYP11B2 (0.85) | CYP11B2 | |
| SCHEMBL17207554 | 0.74 | CYP11B2 (0.79) | CYP11B2 | |
| SCHEMBL17207663 | 0.74 | CYP11B2 (0.73) | CYP11B2 | |
| SCHEMBL18489968 | 0.73 | CYP11B2 (0.84) | CYP11B2 | |
| SCHEMBL28557913 | 0.73 | CYP11B2 (0.84) | CYP11B2 | |
| SCHEMBL28557916 | 0.73 | CYP11B2 (0.84) | CYP11B2 | |
| SCHEMBL15578305 | 0.73 | SCN9A (0.60) | CYP11B2ALDH1A1 | |
| SCHEMBL20514041 | 0.73 | CYP11B2 (0.68) | CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | CYP11B2 8/4885ALDH1A1 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.