Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22239258 | 0.92 | HRH3 (0.41) | HRH3GRIN2BGRIN1 | |
| SCHEMBL29036770 | 0.80 | CYP2D6 (0.52) | HRH3 | |
| SCHEMBL22239201 | 0.78 | HRH3 (0.47) | HRH3 | |
| SCHEMBL29036764 | 0.75 | NOS3 (0.46) | HRH3 | |
| SCHEMBL29036763 | 0.75 | CYP2D6 (0.51) | HRH3 | |
| SCHEMBL24136402 | 0.74 | GRIN2B (0.39) | GRIN2BGRIN1 | |
| SCHEMBL29036801 | 0.74 | HRH3 (0.49) | HRH3 | |
| SCHEMBL22239303 | 0.72 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL24136364 | 0.72 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL29346469 | 0.72 | GRIN2B (0.67) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-A1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |