SCHEMBL29036770

SCHEMBL29036770

Oc1ccc(CCCN2CCCCC2)nc1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.52
CYP1A2 P05177 1/20 0.52
HRH3 Q9Y5N1 12/20 0.50
CTSK P43235 1/20 0.41
KCNH2 Q12809 1/20 0.41
ESR1 P03372 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
HRH4 Q9H3N8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29036763 0.95 CYP2D6 (0.51) CYP2D6CYP1A2HRH3SIGMAR1HRH4
SCHEMBL29036781 0.90 CYP1A2 (0.63) CYP2D6CYP1A2HRH3ESR1SIGMAR1
SCHEMBL29036764 0.86 NOS3 (0.46) CYP2D6CYP1A2HRH3ESR1SIGMAR1
SCHEMBL29036801 0.85 HRH3 (0.49) CYP1A2HRH3KCNH2SIGMAR1
SCHEMBL29036806 0.82 SIGMAR1 (0.49) CYP2D6CYP1A2HRH3ESR1SIGMAR1
SCHEMBL15759178 0.81 CYP1A2 (0.56) CYP2D6CYP1A2HRH3KCNH2SIGMAR1
SCHEMBL29216736 0.81 SIGMAR1 (0.44) CYP2D6CYP1A2HRH3SIGMAR1
SCHEMBL1856187 0.80 HRH3 (0.55) CYP2D6CYP1A2HRH3KCNH2
SCHEMBL22239262 0.80 HRH3 (0.42) HRH3
SCHEMBL12726995 0.79 HRH3 (0.51) CYP2D6CYP1A2HRH3CTSKKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN disclosed