Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 10/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770122 | 0.91 | AXL (0.33) | CNR2ACACBNTRK1MAP4K1 | |
| SCHEMBL17777016 | 0.91 | AXL (0.33) | CNR2ACACBNTRK1MAP4K1 | |
| SCHEMBL17770116 | 0.91 | AXL (0.33) | CNR2ACACBNTRK1MAP4K1 | |
| SCHEMBL17770184 | 0.91 | AXL (0.33) | CNR2ACACBNTRK1MAP4K1 | |
| SCHEMBL19736506 | 0.91 | FDPS (0.40) | CNR2ACACBNTRK1MAP4K1GSK3B | |
| SCHEMBL19736307 | 0.91 | RPS6KA3 (0.42) | CNR2ACACBRPS6KA3NPC1ALDH1A1 | |
| SCHEMBL19736162 | 0.90 | CNR2 (0.35) | CNR2ACACBNTRK1MAP4K1FGFR1 | |
| SCHEMBL19736429 | 0.89 | FGFR1 (0.39) | ACACBNTRK1MAP4K1FGFR1 | |
| SCHEMBL17770220 | 0.89 | OPRK1 (0.39) | OPRK1GSK3BCDK5DYRK1ACDK5R1 | |
| SCHEMBL17776945 | 0.89 | OPRK1 (0.39) | OPRK1GSK3BCDK5DYRK1ACDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |