Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770342 | 0.92 | IDO1 (0.36) | KIF11IDO1AGXTMAPT | |
| SCHEMBL769992 | 0.85 | IDO1 (0.32) | IDO1AGXTMAPT | |
| SCHEMBL2223979 | 0.75 | KIF11 (0.41) | KIF11PDK2MKNK1MKNK2IDO1 | |
| SCHEMBL12805079 | 0.75 | KIF11 (0.41) | KIF11PDK2MKNK1MKNK2IDO1 | |
| SCHEMBL2223968 | 0.74 | KIF11 (0.40) | KIF11PDK2MKNK1MKNK2RXRA | |
| SCHEMBL2223991 | 0.72 | TACR1 (0.37) | — | |
| SCHEMBL12490182 | 0.70 | ALDH1A1 (0.39) | KIF11PDK2IDO1RXRARXRB | |
| SCHEMBL11310791 | 0.65 | MKNK1 (0.56) | KIF11PDK2MKNK1MKNK2 | |
| SCHEMBL679970 | 0.65 | MKNK1 (0.56) | KIF11PDK2MKNK1MKNK2 | |
| SCHEMBL1081720 | 0.65 | CA1 (0.39) | IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516389-B1 | FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES CO (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8975436-B2 | Fluorinated arylene-containing compounds, methods, and polymers prepared therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2516389-A1 | FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM | 3M Innovative Properties Company (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20120252997-A1 | FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2012-10-04 | — | — | US | disclosed |
| WO-2011087717-A1 | FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252997-A1 | FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM | WASF2, PFAS, FLI1 | KIF11 1402/4885PDK2 2227/4885MKNK1 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.