SCHEMBL2223988

SCHEMBL2223988

CC(F)C(F)(F)C(F)(F)OC(F)(F)c1ccccc1-c1ccc(CCl)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.35
SLC13A5 Q86YT5 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
MME P08473 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769991 0.80 MAOB (0.30)
SCHEMBL566000 0.73 SLC13A5 (0.52) CNR2SLC13A5PPARGPPARAMME
SCHEMBL2223970 0.69 KIF11 (0.37)
SCHEMBL770341 0.67 PTPN5 (0.34)
SCHEMBL10896799 0.65 MAOB (0.45)
SCHEMBL2223991 0.65 TACR1 (0.37) FFAR4
SCHEMBL13017118 0.64 PPARG (0.52) CNR2SLC13A5PPARGPPARAMME
SCHEMBL11647065 0.62 CYP2A6 (0.46) PPARGPPARA
SCHEMBL27823295 0.62 HSD11B1 (0.36) CNR2PPARGPPARAFFAR4
SCHEMBL11731370 0.62 KMT2A (0.42) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516389-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-10-31 EP disclosed
WO-2011087717-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed