SCHEMBL2223989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15656299	0.90	HRH3 (0.40)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL2226055	0.89	HTR3E (0.41)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	Hydrochloric Acid SCHEMBL2224855	0.88	HTR3E (0.40)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL14632724	0.86	MEN1 (0.40)	ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
	SCHEMBL2223101	0.86	MEN1 (0.36)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL2225709	0.85	KDM4E (0.42)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL2222328	0.85	MLLT1 (0.36)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL2223713	0.84	SIGMAR1 (0.36)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL14632833	0.82	ALDH1A1 (0.39)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	Water SCHEMBL2273702	0.82	ALDH1A1 (0.38)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.