Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346329 | 1.00 | MTNR1A (0.46) | MTNR1AMTNR1BPRKCGPRKCAPRKCD | |
| SCHEMBL22434211 | 0.81 | OPRM1 (0.38) | OPRM1OPRK1OPRL1OPRD1NOTUM | |
| SCHEMBL19047038 | 0.81 | OPRM1 (0.38) | OPRM1OPRK1OPRL1OPRD1NOTUM | |
| SCHEMBL10173839 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BADRA2AADRA2BADRA2C | |
| SCHEMBL13345363 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BADRA2AADRA2BADRA2C | |
| SCHEMBL20980913 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BADRA2AADRA2BADRA2C | |
| SCHEMBL19844808 | 0.75 | MAOA (0.46) | OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL19368171 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BPRKCGPRKCAPRKCD | |
| SCHEMBL4798469 | 0.74 | SLC6A2 (0.49) | MTNR1AMTNR1BADRA2AADRA2BADRA2C | |
| SCHEMBL1450544 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119784-B1 | BENZIMIDAZOLE DERIVATIVES AS ERBB TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | CAPELLA THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |