Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14847482 | 0.80 | CYP2D6 (0.46) | TAAR1POLBCYP2D6MEN1KMT2A | |
| SCHEMBL12846428 | 0.80 | CYP2D6 (0.46) | TAAR1POLBCYP2D6MEN1KMT2A | |
| SCHEMBL10169593 | 0.80 | CYP2D6 (0.46) | TAAR1POLBCYP2D6MEN1KMT2A | |
| SCHEMBL20053566 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2HPGDTDP1 | |
| SCHEMBL3861132 | 0.72 | MAPT (0.41) | TAAR1POLBKMT2AALDH1A1HPGD | |
| SCHEMBL22240437 | 0.71 | ALOX5 (0.49) | POLBKMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8270258 | 0.71 | ALOX5 (0.49) | POLBKMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL20145796 | 0.71 | ALOX5 (0.49) | POLBKMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL13823414 | 0.70 | SMN1; SMN2 (0.37) | TAAR1POLBCYP2D6MEN1KMT2A | |
| SCHEMBL6871392 | 0.63 | CYP2D6 (0.50) | TAAR1POLBCYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3385263-B1 | PYRIMIDINYL TYROSINE KINASE INHIBITORS | BIOGEN MA INC (US) | 2020-07-22 | — | — | EP | disclosed |