SCHEMBL22241533

SCHEMBL22241533

COc1ccc(C(CC(N)=O)n2ccnc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.58
KMT2A Q03164 3/20 0.55
TNF P01375 1/20 0.54
CYP24A1 Q07973 4/20 0.53
CYP26A1 O43174 1/20 0.51
CYP17A1 P05093 2/20 0.50
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.45
P4HB P07237 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18123005 0.88 CYP19A1 (0.59) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL20830319 0.88 CYP19A1 (0.59) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL19054885 0.87 CYP19A1 (0.58) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL21419663 0.85 CYP19A1 (0.56) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL20390011 0.84 CYP19A1 (0.54) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL21419653 0.78 CYP19A1 (0.47) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL27618666 0.77 CYP19A1 (0.76) CYP19A1KMT2ACYP26A1CYP17A1MEN1
SCHEMBL22241536 0.76 CYP19A1 (0.46) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL21419725 0.76 CYP24A1 (0.49) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1
SCHEMBL18516675 0.76 CYP17A1 (0.50) CYP19A1KMT2ACYP24A1CYP26A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683210-A1 COMPOUND, EPOXY CURING CATALYST AND METHOD FOR PRODUCING COMPOUND Tokyo Ohka Kogyo Co., Ltd. (JP) 2020-07-22 EP disclosed