SCHEMBL27618666

SCHEMBL27618666

COc1ccc(C(n2ccnc2)n2ccnc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.76
CYP26A1 O43174 2/20 0.52
KMT2A Q03164 3/20 0.50
P4HB P07237 1/20 0.50
CYP17A1 P05093 1/20 0.48
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
MEN1 O00255 2/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14397071 0.85 CYP19A1 (0.59) CYP19A1CYP26A1KMT2ACYP17A1MEN1
SCHEMBL19054896 0.85 CYP19A1 (0.73) CYP19A1CYP26A1KMT2AP4HBCYP17A1
SCHEMBL19999188 0.82 CYP19A1 (0.69) CYP19A1CYP26A1KMT2AP4HBCYP17A1
SCHEMBL19999180 0.81 CYP19A1 (0.88) CYP19A1CYP26A1KMT2AP4HBCYP17A1
SCHEMBL9490860 0.80 CYP19A1 (0.66) CYP19A1CYP26A1KMT2AP4HBCYP17A1
SCHEMBL19999183 0.77 CYP19A1 (0.62) CYP19A1CYP26A1CYP1A2CYP3A4
SCHEMBL22241533 0.77 CYP19A1 (0.58) CYP19A1CYP26A1KMT2AP4HBCYP17A1
SCHEMBL1507768 0.76 CYP19A1 (0.78) CYP19A1P4HBCYP11B1CYP11B2
SCHEMBL5321586 0.76 CYP19A1 (0.71) CYP19A1CYP26A1KMT2ACYP17A1CYP11B1
SCHEMBL18123005 0.75 CYP19A1 (0.59) CYP19A1CYP26A1KMT2ACYP17A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100573322-C The inorganic device in plane 3M INNOVATIVE PROPERTIES CO (US) 2009-12-23 CN disclosed
CN-1688936-A Planar inorganic device 3M INNOVATIVE PROPERTIES CO (US) 2005-10-26 CN disclosed