SCHEMBL222426

SCHEMBL222426

CCCCCCCCCCCCCCCCCCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.58
CYP3A4 P08684 3/20 0.55
GAA P10253 4/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
TSHR P16473 2/20 0.50
TP53 P04637 2/20 0.49
HIF1A Q16665 2/20 0.49
MEN1 O00255 1/20 0.49
GMNN O75496 1/20 0.49
GABBR2 O75899 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
NFKB1 P19838 1/20 0.49
MAPK1 P28482 1/20 0.49
CYP2C19 P33261 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105323 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL3818554 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL424334 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL421708 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL5151481 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL225812 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL426302 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL423476 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL421859 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1
SCHEMBL424431 1.00 PTGS2 (0.58) PTGS2CYP3A4GAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113126431-B Photosensitive bismaleimide composition 罗门哈斯电子材料有限责任公司 2024-10-01 CN claimed
CN-114940824-B Vibrating diaphragm of sound generating device, manufacturing method of vibrating diaphragm and sound generating device 歌尔股份有限公司 2024-03-08 CN claimed
US-11639398-B2 Photosensitive bismaleimide composition ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-05-02 US claimed
CN-113126431-A Photosensitive bismaleimide composition 罗门哈斯电子材料有限责任公司 2021-07-16 CN claimed
US-20210198389-A1 PHOTOSENSITIVE BISMALEIMIDE COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-07-01 US claimed
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2026-04-16 US disclosed
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2025-12-09 US disclosed
CN-113126431-B Photosensitive bismaleimide composition 罗门哈斯电子材料有限责任公司 2024-10-01 CN disclosed
CN-114940824-B Vibrating diaphragm of sound generating device, manufacturing method of vibrating diaphragm and sound generating device 歌尔股份有限公司 2024-03-08 CN disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
US-11639398-B2 Photosensitive bismaleimide composition ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-05-02 US disclosed
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2023-02-14 US disclosed
EP-0351360-A1 Process for preparing thermally stabilized polyolefins CIBA-GEIGY AG (CH) 1990-01-17 EP disclosed
US-4197372-A CRASH PADDING KRAUSE MILLING COMPANY (US) 1980-04-08 US disclosed
EP-0003161-A1 A process for preparing polyurethane foams, and the prepared foams Krause Milling Company (US) 1979-07-25 EP disclosed
EP-0003160-A1 A process for preparing semi-flexible polyurethane foams, and the prepared foams Krause Milling Company (US) 1979-07-25 EP disclosed
US-4156759-A ANTIOXIDANT KRAUSE MILLING COMPANY (US) 1979-05-29 US disclosed
US-4000221-A A PHENOL, AN ORGANIC PHOSPHITE, POLYMER OF CONJUGATED DIENE AND MONO-VINYL AROMATIC COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1976-12-28 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 PTGS2 2647/4885CYP3A4 3582/4885GAA 61/4885
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 PTGS2 2647/4885CYP3A4 3582/4885GAA 61/4885
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MPO, CYC1, CBR1 PTGS2 1437/4885CYP3A4 987/4885GAA 624/4885
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 PTGS2 2647/4885CYP3A4 3582/4885GAA 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.