Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685140 | 1.00 | LMNA (0.35) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL6757990 | 0.85 | — | — | |
| SCHEMBL6757981 | 0.85 | — | — | |
| SCHEMBL679519 | 0.85 | — | — | |
| SCHEMBL14367741 | 0.82 | LMNA (0.38) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL18069727 | 0.82 | LMNA (0.43) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL26685135 | 0.76 | MEN1 (0.34) | CYP2C9TRPA1TRPM8 | |
| SCHEMBL7751563 | 0.76 | TRPA1 (0.40) | TRPA1TRPM8 | |
| SCHEMBL6757609 | 0.76 | TRPA1 (0.40) | TRPA1TRPM8 | |
| SCHEMBL6758017 | 0.76 | TRPA1 (0.40) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147798-A1 | CYCLIC MOLECULES AS BRUTON'S TYROSINE KINASE INHIBITOR | 明慧医药（上海）有限公司 | 2020-07-23 | — | — | WO | disclosed |