Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757990 | 0.97 | — | — | |
| SCHEMBL6757981 | 0.97 | — | — | |
| SCHEMBL679519 | 0.97 | — | — | |
| SCHEMBL14367741 | 0.94 | LMNA (0.38) | LMNACYP2C9TRPA1TRPM8PIK3CD | |
| SCHEMBL10297514 | 0.84 | TRPA1 (0.37) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL1270382 | 0.83 | NOS3 (0.33) | — | |
| SCHEMBL22243252 | 0.82 | LMNA (0.35) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL26685140 | 0.82 | LMNA (0.35) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL10409614 | 0.80 | DPP4 (0.40) | LMNACYP2C9TRPA1TRPM8 | |
| SCHEMBL7751563 | 0.80 | TRPA1 (0.40) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | MODERNATX, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-10563195-B2 | Phosphate replacement mRNA cap analogs | MODERNATX, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| US-10428106-B2 | Phosphate replacement mRNA cap analogs | MODERNATX, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20160264554-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428106-B2 | Phosphate replacement mRNA cap analogs | RNGTT, RNMT, CPSF6 | LMNA 3740/4885CYP2C9 4677/4885TRPA1 4843/4885 |
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | RNGTT, RNMT, CPSF6 | LMNA 3607/4885CYP2C9 4655/4885TRPA1 4851/4885 |
| US-20160264554-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK13, CDK3, CDK12 | LMNA 1208/4885CYP2C9 1056/4885TRPA1 4524/4885 |
| US-10563195-B2 | Phosphate replacement mRNA cap analogs | RNGTT, RNMT, CPSF6 | LMNA 3607/4885CYP2C9 4655/4885TRPA1 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.