SCHEMBL2224364

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL160054	0.83	MAPT (0.50)	MAPTLMNACA12CA1CA2
	SCHEMBL9944379	0.83	P2RX7 (0.56)	MAPTLMNACA12CA1CA2
	SCHEMBL28241780	0.83	MAPT (0.50)	MAPTLMNACA12CA1CA2
	SCHEMBL28558153	0.81	MAPT (0.49)	MAPTLMNACA12CA1CA2
	SCHEMBL9944381	0.81	NAPRT (0.56)	MAPTLMNACA12CA1CA2
	SCHEMBL2223051	0.81	LMNA (0.56)	MAPTLMNAPOLBNPSR1KMT2A
	SCHEMBL12517053	0.81	NAPRT (0.56)	MAPTLMNACA12CA1CA2
	SCHEMBL31185958	0.80	KDM4E (0.57)	LMNAPOLBKMT2AKDM4EL3MBTL1
	SCHEMBL107721	0.80	KDM4E (0.57)	LMNAPOLBKMT2AKDM4EL3MBTL1
	SCHEMBL9944383	0.80	MAPT (0.51)	MAPTLMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.