Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224364 | 0.81 | MAPT (0.50) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL28241780 | 0.81 | MAPT (0.50) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL160054 | 0.81 | MAPT (0.50) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL9944379 | 0.81 | P2RX7 (0.56) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL1340967 | 0.81 | MAP2K1 (0.57) | LMNAPOLBKMT2AKDM4EL3MBTL1 | |
| SCHEMBL12517053 | 0.80 | NAPRT (0.56) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL9944381 | 0.80 | NAPRT (0.56) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL2223051 | 0.80 | LMNA (0.56) | MAPTLMNAPOLBNPSR1KMT2A | |
| SCHEMBL9944383 | 0.79 | MAPT (0.51) | MAPTLMNANPC1POLBNPSR1 | |
| SCHEMBL28428672 | 0.79 | KDM4E (0.61) | MAPTLMNANPC1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812098-A | Preparation method and medical application of unsaturated cyclic amine pyridine disulfide derivative | 北京沃邦医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |