Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31050198 | 0.86 | PDE2A (0.38) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL1450228 | 0.82 | PARP10 (0.39) | SRD5A2ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL4578492 | 0.82 | SRD5A2 (0.57) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL1124738 | 0.80 | CES2 (0.57) | SRD5A2EPHX2MEN1KMT2AKIF11 | |
| SCHEMBL11583494 | 0.79 | HDAC1 (0.55) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL28887251 | 0.79 | KMT2A (0.38) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL12163592 | 0.79 | HDAC1 (0.48) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL284242 | 0.79 | EPHX2 (0.66) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL21837346 | 0.77 | HDAC1 (0.53) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 | |
| SCHEMBL4805637 | 0.77 | SRD5A2 (0.52) | HDAC1SRD5A2EPHX2NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597371-A | Novel polymer, resin composition containing the same, and molded article thereof | 日本曹达株式会社 | 2024-02-23 | — | — | CN | disclosed |
| WO-2011083413-A1 | PIPERAZINES AS ANTIMALARIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-07-14 | — | — | WO | disclosed |