Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225550 | 0.89 | S1PR1 (0.56) | S1PR1ALDH1A1TP53HSD17B10 | |
| SCHEMBL2224494 | 0.89 | S1PR1 (0.47) | S1PR1ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL2227168 | 0.86 | S1PR1 (0.52) | S1PR1ALDH1A1TP53HPGDNFKB1 | |
| SCHEMBL2224156 | 0.85 | S1PR1 (0.47) | S1PR1ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL14796988 | 0.84 | S1PR1 (0.70) | S1PR1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL2222401 | 0.83 | S1PR1 (0.49) | S1PR1ALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL2222853 | 0.82 | S1PR1 (0.58) | S1PR1ALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL2224142 | 0.82 | S1PR1 (0.51) | S1PR1ALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL2269044 | 0.81 | S1PR1 (0.55) | S1PR1ALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL2223341 | 0.81 | S1PR1 (0.54) | S1PR1ALDH1A1TP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |