⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908513 | 0.52 | — | — | |
| SCHEMBL26690481 | 0.52 | — | — | |
| SCHEMBL8731685 | 0.51 | CYP3A4 (0.43) | — | |
| SCHEMBL3630532 | 0.51 | CYP3A4 (0.43) | — | |
| SCHEMBL3150036 | 0.51 | CYP3A4 (0.43) | — | |
| SCHEMBL1687833 | 0.49 | — | — | |
| SCHEMBL8981770 | 0.49 | — | — | |
| SCHEMBL20320368 | 0.49 | ENO1 (0.32) | — | |
| SCHEMBL14458060 | 0.49 | MAPT (0.36) | — | |
| SCHEMBL31398713 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001270-A1 | PLANT EXTRACTS ENRICHED WITH IPOLAMIIDE DERIVATIVES AS IMMUNOSUPPRESSANTS FOR TREATING IMMUNOLOGICAL DISORDERS AND VITILIGO | Aché Laboratórios Farmacêuticos S.A. (BR) | 2022-05-25 | — | — | EP | disclosed |
| EP-3583103-B1 | PLANT EXTRACTS ENRICHED WITH IPOLAMIIDE DERIVATIVES AS IMMUNOSUPPRESSANTS FOR TREATING IMMUNOLOGICAL DISORDERS | ACHE LABORATORIOS FARMACEUTICOS SA (BR) | 2022-01-12 | — | — | EP | disclosed |
| US-20200231561-A1 | PLANT EXTRACTS ENRICHED WITH IPOLAMIIDE DERIVATIVES AS IMMUNOSUPPRESSANTS FOR TREATING IMMUNOLOGICAL DISORDERS | ACHE LABORATORIOS FARMACEUTICOS S.A. (BR) | 2020-07-23 | — | — | US | disclosed |