Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ELOVL1 | Q9BW60 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23719191 | 0.88 | MAPT (0.54) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL22828578 | 0.84 | LMNA (0.66) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL22246858 | 0.77 | LMNA (0.74) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10616565 | 0.75 | MAPT (0.50) | LMNAMAPTHTTHSD17B10TSHR | |
| SCHEMBL22828685 | 0.74 | MAPT (0.54) | MAPTHTTHSD17B10TSHRL3MBTL1 | |
| SCHEMBL23719149 | 0.71 | MAPK10 (0.51) | MAPTALDH1A1HTTRAB9A | |
| SCHEMBL3307413 | 0.71 | ALDH1A1 (0.63) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10764251 | 0.69 | SCN5A (0.56) | LMNAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL14880165 | 0.69 | SCN5A (0.56) | LMNAKDM4ERAB9A | |
| SCHEMBL13494653 | 0.69 | L3MBTL1 (0.61) | LMNAALDH1A1SMN1; SMN2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150417-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2020-07-23 | — | — | WO | disclosed |