Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25120811 | 0.81 | ATR (0.45) | ALDH1A1EPHX1EPHX2MEN1RAB9A | |
| SCHEMBL25120805 | 0.80 | MERTK (0.34) | MERTKPKM | |
| SCHEMBL22246774 | 0.73 | GAA (0.35) | MERTKALDH1A1GAAMEN1MAPT | |
| SCHEMBL23719135 | 0.72 | EPHX1 (0.43) | MERTKALDH1A1PKMEPHX1EPHX2 | |
| SCHEMBL29220635 | 0.66 | NAAA (0.58) | MERTKENPP2EPHX1EPHX2MAPT | |
| SCHEMBL22246679 | 0.65 | ALDH1A1 (0.54) | ALDH1A1GAAMEN1MAPTRAB9A | |
| SCHEMBL28697839 | 0.65 | GAA (0.58) | ALDH1A1GAARAB9A | |
| SCHEMBL22407656 | 0.63 | KDM4E (0.63) | ALDH1A1PKMGAAHTTMEN1 | |
| SCHEMBL22407647 | 0.63 | KDM4E (0.63) | ALDH1A1PKMGAAHTTMEN1 | |
| SCHEMBL1498813 | 0.62 | RAB9A (0.38) | MERTKALDH1A1EPHX1EPHX2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150417-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2020-07-23 | — | — | WO | disclosed |