Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151480 | 0.87 | — | — | |
| SCHEMBL25522286 | 0.81 | — | — | |
| SCHEMBL26328069 | 0.80 | — | — | |
| SCHEMBL25910486 | 0.79 | KDM4E (0.37) | KDM4EOPRM1OPRK1OPRL1GAA | |
| SCHEMBL16263320 | 0.78 | KDM4E (0.35) | KDM4EOPRM1OPRK1OPRL1GAA | |
| SCHEMBL13643929 | 0.78 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9959957 | 0.77 | KDM4E (0.36) | KDM4EOPRM1OPRK1OPRL1GAA | |
| SCHEMBL25019036 | 0.76 | KDM4E (0.31) | KDM4EGAA | |
| SCHEMBL8759751 | 0.76 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL27756281 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231597-A1 | BICYLIC COMPOUND ACTING AS AN INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231597-A1 | BICYLIC COMPOUND ACTING AS AN INHIBITOR | RORC, RORB, RORA | KDM4E 3668/4885OPRM1 3278/4885OPRK1 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.