Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249180 | 0.85 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248398 | 0.85 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248447 | 0.82 | SIGMAR1 (0.43) | SIGMAR1ROCK2DRD3KCNH2MCHR1 | |
| SCHEMBL22248444 | 0.81 | MCHR1 (0.40) | ROCK2KCNH2MCHR1 | |
| SCHEMBL22248445 | 0.80 | SIGMAR1 (0.30) | SIGMAR1ROCK2 | |
| SCHEMBL22248442 | 0.80 | MCHR1 (0.33) | SIGMAR1ROCK2DRD3MCHR1CYP11B2 | |
| SCHEMBL22248436 | 0.79 | ROCK2 (0.35) | ROCK2MCHR1 | |
| SCHEMBL22249183 | 0.77 | ROCK2 (0.37) | ROCK2MCHR1 | |
| SCHEMBL22249170 | 0.77 | ROCK2 (0.35) | ROCK2MCHR1 | |
| Hydrochloric Acid SCHEMBL30276573 | 0.77 | DRD3 (0.32) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |