Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249163 | 0.84 | ROCK2 (0.39) | HRH3ROCK2MCHR1KCNH2 | |
| SCHEMBL22248443 | 0.82 | SIGMAR1 (0.33) | SIGMAR1DRD3ROCK2MCHR1KCNH2 | |
| SCHEMBL22248679 | 0.79 | DRD3 (0.35) | SIGMAR1DRD3GPR119MCHR1 | |
| SCHEMBL22248445 | 0.78 | SIGMAR1 (0.30) | SIGMAR1ROCK2 | |
| SCHEMBL25532099 | 0.75 | LGMN (0.36) | ROCK2 | |
| SCHEMBL25532205 | 0.74 | ROCK2 (0.42) | ROCK2MCHR1KCNH2 | |
| SCHEMBL22254172 | 0.73 | LMNA (0.36) | ROCK2KCNH2 | |
| SCHEMBL22235717 | 0.73 | XDH (0.34) | ROCK2MCHR1KCNH2 | |
| SCHEMBL22248654 | 0.73 | ROCK2 (0.50) | SIGMAR1DRD3HRH3ROCK2 | |
| SCHEMBL22254180 | 0.72 | MCHR1 (0.35) | SIGMAR1DRD3ROCK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |