Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 12/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249105 | 1.00 | ROCK2 (0.37) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22249113 | 0.95 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2 | |
| SCHEMBL22248292 | 0.92 | DGAT1 (0.33) | ROCK2POLBENPP2 | |
| SCHEMBL22235671 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22249150 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22248311 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22248329 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22254145 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22248341 | 0.91 | ROCK2 (0.38) | ROCK2POLBFAAHENPP2CA12 | |
| SCHEMBL22254537 | 0.89 | ROCK2 (0.39) | ROCK2POLBFAAHENPP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |