Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249108 | 0.95 | ROCK2 (0.37) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL22249105 | 0.95 | ROCK2 (0.37) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL25532024 | 0.89 | ROCK2 (0.40) | ROCK2ENPP2POLBKCNH2 | |
| SCHEMBL25553050 | 0.89 | ROCK2 (0.40) | ROCK2ENPP2POLBKCNH2 | |
| SCHEMBL22254547 | 0.89 | ROCK2 (0.40) | ROCK2ENPP2POLBKCNH2 | |
| SCHEMBL22248292 | 0.89 | DGAT1 (0.33) | ROCK2ENPP2DGAT1POLBKCNH2 | |
| SCHEMBL22249065 | 0.87 | ROCK2 (0.37) | ROCK2DGAT1FAAHTEAD1 | |
| SCHEMBL22254546 | 0.87 | ROCK2 (0.41) | ROCK2ENPP2UTS2RPOLBKCNH2 | |
| SCHEMBL22254545 | 0.87 | ROCK2 (0.41) | ROCK2ENPP2UTS2RPOLBKCNH2 | |
| SCHEMBL25532018 | 0.87 | ROCK2 (0.41) | ROCK2ENPP2UTS2RPOLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |