Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 6/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
| ▸ | PAICS | P22234 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249152 | 1.00 | ROCK2 (0.38) | ROCK2ENPP2POLBKDM1AMAOB | |
| SCHEMBL22249145 | 0.91 | ROCK2 (0.36) | ROCK2ENPP2POLBKDM1AMAOB | |
| SCHEMBL22248357 | 0.89 | ROCK2 (0.35) | ROCK2ENPP2FAAHABL1RIN1 | |
| SCHEMBL22254537 | 0.88 | ROCK2 (0.39) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL22248333 | 0.87 | ROCK2 (0.36) | ROCK2ENPP2FAAHABL1RIN1 | |
| SCHEMBL22248499 | 0.87 | ROCK2 (0.36) | ROCK2FAAH | |
| SCHEMBL22235671 | 0.86 | ROCK2 (0.38) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL22249150 | 0.86 | ROCK2 (0.38) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL22248329 | 0.86 | ROCK2 (0.38) | ROCK2ENPP2POLBFAAH | |
| SCHEMBL22248411 | 0.85 | CXCR4 (0.39) | POLBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |